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Our vision is to develop a world-class web portal, where the very latest in academic and industrial research can be accessed, downloaded and shared by all.

The hub of academia that has no boundaries and sponsors an ‘anything-goes’ policy with researchers from all fronts, including those in public and private institutions, corporations, NGOs etc.

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A young but growing community with diverse fields, researchers, students, industry mentors, partners etc.The potential of posttherapy imaging assessment to monitor response to multidrug chemotherapy for head and neck cancer patients.
Our aim was to assess the ability of posttherapy imaging to monitor response to multimodal therapy of head and neck cancer patients. Lymph node metastases are one of the most important prognostic factors for head and neck cancer patients. The presence of regional lymph node metastases can be assessed pretherapy with a high accuracy by means of contrast-enhanced ultrasonography and other tomographic modalities. We examined in a prospective study 35 patients with primary squamous cell carcinoma of the head and neck by contrast-enhanced ultrasonography, CT and MRI. All patients received standardized multimodal therapy consisting of induction chemotherapy, radiotherapy and surgery. Axial and sagittal T1-weighted and axial T2-weighted and STIR-weighted MRI images were obtained before and after induction chemotherapy and afterwards at the re-evaluation. After induction chemotherapy alone, one of the 35 patients showed a complete response, one patient a partial response and one patient a minor response. After radiotherapy alone, no patient showed a complete response, two patients a partial response and two patients a minor response. After combined therapy, one patient showed a complete response, one patient a partial response and one patient a minor response. Posttherapy imaging revealed a higher number of residual tumour lesions than pretherapy imaging. In 17 (50%) of the 35 patients a residual disease was found. Posttherapy assessment of the neck still allows assessment of the tumour response after multimodal therapy of squamous cell carcinoma of the head and neck. In a subset of patients, the complete disappearance of tumour tissue was shown by posttherapy imaging. The data indicate that posttherapy imaging is a suitable method to monitor response to multimodal therapy.Follow the author of this article
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